The Premier League returns this weekend with four of the big six in direct competition, Manchester City hosting Brighton AGAIN and a crunch clash towards the bottom between Coventry and Sunderland.The slate starts with a huge game at Stamford Bridge between Chelsea and Manchester United while Sundays sole game features Liverpool at home to an Arsenal side desperate to make amends for their penalty shootout exit at the hands of League Two strugglers Fleetwood.As always, bet365 will offer odds for players on all the games, as well as other fixtures from the EFL, Europe and the rest of the world.Here, we identify five wagers you may not have considered! All odds supplied by bet365 and correct as of 1300 on Thursday, October 29Fernandes to finally fire for beleaguered Carrick?It has not been a great week for Bruno Fernandes, Michael Carrick or, indeed, anyone of a Manchester United persuasion.Last Sundays 3-0 humbling by Bournemouth at Old Trafford was dominated by a narrative that saw Fernandes spend the afternoon on the bench after criticising Carricks tactics in the aftermath of the midweek defeat at Como.United missed the Portugueses guile in midfield as the Cherries cruised to a win that most thought would end Carricks tenure. As it was, he received a stay of execution while talks aimed at a reconciliation between United coach and captain were a reported success, meaning Fernandes will return to the starting XI for Saturdays clash at Chelsea.Fernandes has a point to prove. Will he mark his return with a bang?Bruno Fernandes to score anytime is 3/1Bruno Fernandes to score the opening goal is 10/1Not-so-cool Cole to see red again?Cole Palmer has always come across as laid back to the point of being horizontal. But the England internationals disciplinary record displays a more fiery side.Palmer has been booked 21 times in his club career and received two yellow cards in quick succession and a subsequent red against Tottenham on Saturday.His dismissal compounded a miserable evening for Xabi Alonsos men, who were beaten 2-0 by their London rivals.If there is a positive for Palmer it is that he served his one-game domestic ban at Liverpool in the EFL Cup in midweek and is available to face United.Surely he will keep his temper in check against the club he supported as a boy?Cole Palmer to be sent-off against Manchester United is 66/1Cole Palmer to be booked against Manchester United is 7/2Arsenal to suffer more spot-kick woe?Arsenal were expected to enjoy their evening by the seaside but the trip to Fleetwoods compact Highbury Stadium turned into the stuff of nightmares.Mikel Arteta made changes but his starting XI still contained seven full internationals, including World Cup winner Martin Zubimendi. As the match progressed he also had the luxury of bringing on England trio Ben White, Ezri Konsa and Eberechi Eze, as well as Bruno Guimaraes and Martin Odegaard.By the time the game went to penalties, they werent far from full-strength, albeit down to 10 men following the harsh dismissal of teenager Max Dowman.Guimaraes was the guilty man in the shoot-out, seeing his tame effort saved by home goalkeeper Jay Lynch.Will Guimaraes, who also missed his last spot-kick playing for Brazil against Norway at the World Cup, step up again if Arsenal are awarded a penalty at Anfield?Arsenal to miss a penalty at Liverpool is 22/1Arsenal to score a penalty at Liverpool is 7/1Tottenham target timely trioThe mood music has changed at Tottenham. Previously a funereal march, it is now a Beethoven symphony.Wins against Coventry and Chelsea have transformed the prospects of Roberto De Zerbis side to the point where a Champions League push is now being discussed as a genuine possibility.That may be some way off but they face a dismal Crystal Palace side this weekend and will fancy their chances of winning a third Premier League game on the trot for the first time since February 2025.Seeing off the Eagles will prompt the cockerel to chirp even louder.Tottenham to beat Crystal Palace is 1/2Bungling Barry to find his shooting boots?Everton have lacked a quality striker for some time. Their current top scorer in the Premier League is Thierno Barry.The gangly Frenchman has three but how many could he have had if he could shoot straight?Barry leads the Premier League in one category: most big chances missed, racking up a remarkable 12 in just eight games. He is no Dixie Dean.The Toffees go to Newcastle on Monday Night Football but will Barry bring his A-game?Thierno Barry to have a shot at Newcastle is 1/14Thierno Barry to have a shot on target at Newcastle is 8/11Reasons to play with bet365With bet365, there are always different ways to win, and different ways to approach betting. Its not always as straightforward as Team A beats Team B!As part of their We Know Betting campaign, they have introduced Reasons that demonstrate their excellence in the market.Reason #22 is More Possibilities and this demonstrates that perfectly.Responsible GamblingIt is important that when using any bookmaker and placing bets online, you practice responsible gambling habits wherever possible. This helps to keep your betting a bit of fun and enjoyment.Be sure to use licensed sites to ensure your safety and security, while taking steps to control your gambling habits. Set a budget that you can afford, and keep track of the time you spend placing bets. Utilise the responsible gambling tools that are available at bookmakers, including deposit limits, time reminders, time-outs, and self-exclusions.There are also helplines and resources available, such as GamCare, that bettors can reach out to.GamCare:https://www.gamcare.org.ukNational Gambling Helpline: 0808 8020 133 Topics Arsenal F.C. Chelsea F.C. Everton F.C. Liverpool F.C. Manchester City F.C. Manchester United F.C. Newcastle United F.C. Tottenham Hotspur F.C. 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