EmailPrintOpen Extended ReactionsWeek 1 of the NFL season is officially underway.The 2026 season kicked off Wednesday with the Seattle Seahawks taking down the New England Patriots 13-10 in a Super Bowl rematch, followed by a somewhat surprisingly easy win for the San Francisco 49ers over the Los Angeles Rams on Thursday in Australia.The action continues with a 13-game Sunday slate, with the Buffalo Bills-Houston Texans matchup highlighting the early afternoon games. The Bills come in as slight favorites. The Sunday night game features a classic NFC East rivalry, as the Dallas Cowboys visit the New York Giants as 3-point road favorites.A whopping 12 Week 1 games have spreads of 3.5 points or less. The Los Angeles Chargers are the biggest favorite of the week, laying 9.5 points to the Arizona Cardinals.The week wraps up with Patrick Mahomes making his comeback from a torn ACL when the Kansas City Chiefs (-2.5, 43.5) host the Denver Broncos on "Monday Night Football" (8:15 ET on ABC/ESPN).Here's a look at the odds for every Week 1 game.Note: Odds by DraftKings and subject to change.Jump to:NE-SEA | SF-LAR | TB-CIN | NO-DETNYJ-TEN | BAL-IND | ATL-PIT | CHI-CARCLE-JAX | BUF-HOU | MIA-LV | GB-MINWSH-PHI | ARI-LAC | DAL-NYG | DEN-KCSundayTampa Bay Buccaneers at Cincinnati Bengals (-3.5)1 p.m. ET on Fox, Paycor Stadium, CincinnatiMoneyline: Bengals -198, Buccaneers +164Total: 50.5 pointsFPI favorite: Bengals by 3.2, 62.4% to win outrightNew Orleans Saints at Detroit Lions (-7)1 p.m. ET on Fox, Ford Field, DetroitMoneyline: Lions -310, Saints +250Total: 49.5 pointsFPI favorite: Lions by 6.8, 73.6% to win outrightCheck out each team's futures odds here. For the latest, visit DraftKings.New York Jets at Tennessee Titans (-1.5)1 p.m. ET on CBS, Nissan Stadium, Nashville, Tenn.Moneyline: Titans -125, Jets +105Total: 38.5 pointsFPI favorite: Titans by 2.4, 58.0% to win outrightBaltimore Ravens (-3.5) at Indianapolis Colts1 p.m. ET on CBS, Lucas Oil Stadium, IndianapolisMoneyline: Ravens -175, Colts +145Total: 47.5 pointsFPI favorite: Ravens by 2.5, 59.5% to win outrightAtlanta Falcons at Pittsburgh Steelers (-5.5)1 p.m. ET on Fox, Acrisure Stadium, PittsburghMoneyline: Steelers -230, Falcons +190Total: 41.5 pointsFPI favorite: Steelers by 2.4, 58.0% to win outrightChicago Bears (-3) at Carolina Panthers1 p.m. ET on Fox, Bank of America Stadium, Charlotte, N.C.Moneyline: Bears -170, Panthers +142Total: 47.5 pointsFPI favorite: Bears by 2.7, 58.2% to win outrightCleveland Browns at Jacksonville Jaguars (-8.5)1 p.m. ET on CBS, EverBank Stadium, Jacksonville, Fla.Moneyline: Jaguars -455, Browns +350Total: 39.5 pointsFPI favorite: Jaguars by 7.9, 76.6% to win outrightBuffalo Bills (-1.5) at Houston Texans1 p.m. ET on CBS, NRG Stadium, HoustonMoneyline: Bills -118, Texans -102Total: 44.5 pointsFPI favorite: Bills by 1.0, 53.7% to win outrightFantasy football season is here. Create or join an ESPN league today!Miami Dolphins at Las Vegas Raiders (-3)4:25 p.m. ET on Fox, Allegiant Stadium, Las VegasMoneyline: Raiders -170, Dolphins +142Total: 40.5 pointsFPI favorite: Raiders by 3.0, 61.4% to win outrightGreen Bay Packers at Minnesota Vikings (-1.5)4:25 p.m. ET on CBS, U.S. Bank Stadium, MinneapolisMoneyline: Vikings -122, Packers +102Total: 46.5 pointsFPI favorite: Packers by 1.8, 56.6% to win outrightWashington Commanders at Philadelphia Eagles (-6)4:25 p.m. ET on Fox, Lincoln Financial Field, PhiladelphiaMoneyline: Eagles -250, Commanders +205Total: 44.5 pointsFPI favorite: Eagles by 4.8, 66.3% to win outrightArizona Cardinals at Los Angeles Chargers (-9.5)4:25 p.m. ET on CBS, SoFi Stadium, Inglewood, Calif.Moneyline: Chargers -500, Cardinals +380Total: 47.5 pointsFPI favorite: Chargers by 9.6, 80.2% to win outright Dallas Cowboys (-3) at New York Giants8:20 p.m. ET on NBC, MetLife Stadium, East Rutherford, N.J.Moneyline: Cowboys -162, Giants +136Total: 48.5 pointsFPI favorite: Cowboys by 2.2, 58.3% to win outrightMondayDenver Broncos at Kansas City Chiefs (-2.5)8:15 p.m. ET on ESPN/ABC, GEHA Field at Arrowhead Stadium, Kansas City, Mo.Moneyline: Chiefs -148, Broncos +124Total: 43.5 pointsFPI favorite: Chiefs by 2.5, 57.8% to win outrightThursday's resultSan Francisco 49ers vs. Los Angeles Rams (-3.5)Melbourne Cricket Ground, Melbourne, Australia49ers 27, Rams 7Moneyline: Rams -198, 49ers +164Total: 48.5 pointsFPI favorite: Rams by 2.9, 60.3% to win outrightWednesday's resultNew England Patriots at Seattle Seahawks (-3.5)Lumen Field, SeattleSeahawks 13, Patriots 10Moneyline: Seahawks -180, Patriots +150Total: 45.5 pointsFPI favorite: Seahawks by 3.4, 61.1% to win outright
